Clinical Research Fellow in Respiratory Viral Infections

Job description

Job summary

We are looking for a highlymotivated clinician in training (Internal Medicine/Specialty Registrar Grade orequivalent) with a strong interest in infectious diseases and their preventionto investigate immunity in clinical volunteer studies involving rhinovirus andRSV controlled human infection. You will be part of a multi-disciplinary teamfocusing on human immunity against respiratory viral infections using excitingand unique studies designs alongside cutting-edge laboratory techniques.

Youwill join a dynamic group of clinical fellows, research nurses and scientistsled by Prof Chris Chiu (www.imperial.ac.uk/people/c.chiu)in the Department ofInfectious Disease, to characterise the response to respiratory viruses inolder adults. This will accelerate the development of improved prophylactic interventionsrespiratory viruses, while providing you with unparalleled experience intranslational research, experimental medicine and laboratory analyses.

Main duties of the job

• You will work closely with research nurses, clinical programme manager, other clinical fellows and laboratory scientists to set up and implement human challenge studies to identify determinants of susceptibility and protection against rhinovirus and RSV in older adult volunteers.
• You will manage the clinical studies, working with research nurses and other clinicians to recruit and screen and care for volunteers, administer virus, and obtain samples.

About us

Welcome to Imperial, a global top ten university where scientific imagination leads to world-changing impact.Join us and be part of something bigger. From global health to climate change, AI to business leadership, we navigate some of the world's toughest challenges. Whatever your role, your contribution will have a lasting impact.As a member of our vibrant community of 22,000 students and 8,000 staff, you'll collaborate with passionate minds across nine London campuses and a global network.This is your chance to help shape the future. We hope you'll join us at Imperial.

Job description

Job responsibilities

We anticipate the successful applicant will take up thisposition in February/March 2027. You will hold an honorary contract with theappropriate NHS Trusts and be expected to take on clinical responsibilitiesappropriate to your level of experience expertise, with training instudy-specific areas provided:

Clinical study delivery:

Assist with the setup and day-to-day managementand delivery of respiratory virus human challenge studies.

Assist with recruitment and screening ofvolunteers

Collation, review and sign-off of clinicalinvestigations and other documents for eligibility assessment of studyparticipants.

Provide direct clinical care to studyparticipants admitted for respiratory virus challenge, working with researchnurses and study PIs.

Support delivery of other clinical studies(including trials) within Prof Chius group.

Acting as a point of contact for studyparticipants to provide clinical advice and care before, during and afterchallenge, under the supervision of the study PI.

Co-ordinate the development of study protocolsand associated study documentation.

Prepare safety reports and briefings for thedata safety monitoring committee.

Ensure adherence to the study protocols andcompliance with regulatory requirements.

Work with the rest of the clinical team, inparticular the lead research nurse and clinical project manager, to ensure allclinical research conducted is compliant with Good Clinical Practice.

Academic development, training and supervision:

Participate in the analysis of immune responsesusing cellular and molecular immunology techniques if desired and asappropriate.

Training of study associated personnel.

Troubleshooting issues while maintaining anddeveloping good relationships with researchers and clinicians associated withthe study in a variety of different settings.

Identifying and developing further researchthemes which may be developed within the studies

All staff are expected to contribute to theadministrative work of the study coordinated through the project manager andstudy PIs. The post holder will need to carry out any other reasonable dutiesas required by the study PI, which are likely to increase their breadth ofresearch experience.

Job description
Job responsibilities

We anticipate the successful applicant will take up thisposition in February/March 2027. You will hold an honorary contract with theappropriate NHS Trusts and be expected to take on clinical responsibilitiesappropriate to your level of experience expertise, with training instudy-specific areas provided:

Clinical study delivery:

Assist with the setup and day-to-day managementand delivery of respiratory virus human challenge studies.

Assist with recruitment and screening ofvolunteers

Collation, review and sign-off of clinicalinvestigations and other documents for eligibility assessment of studyparticipants.

Provide direct clinical care to studyparticipants admitted for respiratory virus challenge, working with researchnurses and study PIs.

Support delivery of other clinical studies(including trials) within Prof Chius group.

Acting as a point of contact for studyparticipants to provide clinical advice and care before, during and afterchallenge, under the supervision of the study PI.

Co-ordinate the development of study protocolsand associated study documentation.

Prepare safety reports and briefings for thedata safety monitoring committee.

Ensure adherence to the study protocols andcompliance with regulatory requirements.

Work with the rest of the clinical team, inparticular the lead research nurse and clinical project manager, to ensure allclinical research conducted is compliant with Good Clinical Practice.

Academic development, training and supervision:

Participate in the analysis of immune responsesusing cellular and molecular immunology techniques if desired and asappropriate.

Training of study associated personnel.

Troubleshooting issues while maintaining anddeveloping good relationships with researchers and clinicians associated withthe study in a variety of different settings.

Identifying and developing further researchthemes which may be developed within the studies

All staff are expected to contribute to theadministrative work of the study coordinated through the project manager andstudy PIs. The post holder will need to carry out any other reasonable dutiesas required by the study PI, which are likely to increase their breadth ofresearch experience.

Person Specification

Qualifications

Essential

• Medical degree with GMC registration.

Desirable

• Membership of the Royal College of Physicians or equivalent.

Experience

Essential

• Experience in management of general medical problems, medical emergencies and respiratory infections.
• Demonstrated ability to work collaboratively with other clinicians, nurses and others.

Desirable

• Knowledge of respiratory infections and current developments in the field.
• Knowledge of research methods and statistical procedures.
• Practical experience of clinical studies or trials.
• Experience of the supervision or training of colleagues.
• Experience of presenting to specialist and non-specialist audiences
• Evidence of teaching and teaching support.
• Familiarity with Good Clinical Practice and governance of clinical studies.
• Previous research experience in infectious diseases, virology or immunology.

Person Specification
Qualifications

Essential

• Medical degree with GMC registration.

Desirable

• Membership of the Royal College of Physicians or equivalent.

Experience

Essential

• Experience in management of general medical problems, medical emergencies and respiratory infections.
• Demonstrated ability to work collaboratively with other clinicians, nurses and others.

Desirable

• Knowledge of respiratory infections and current developments in the field.
• Knowledge of research methods and statistical procedures.
• Practical experience of clinical studies or trials.
• Experience of the supervision or training of colleagues.
• Experience of presenting to specialist and non-specialist audiences
• Evidence of teaching and teaching support.
• Familiarity with Good Clinical Practice and governance of clinical studies.
• Previous research experience in infectious diseases, virology or immunology.

Disclosure and Barring Service Check

This post is subject to the Rehabilitation of Offenders Act (Exceptions Order) 1975 and as such it will be necessary for a submission for Disclosure to be made to the Disclosure and Barring Service (formerly known as CRB) to check for any previous criminal convictions.
UK Registration

Applicants must have current UK professional registration. For further information please see

Additional information
Disclosure and Barring Service Check

This post is subject to the Rehabilitation of Offenders Act (Exceptions Order) 1975 and as such it will be necessary for a submission for Disclosure to be made to the Disclosure and Barring Service (formerly known as CRB) to check for any previous criminal convictions.
UK Registration

Applicants must have current UK professional registration. For further information please see

Employer details

Employer name

Imperial College London
Address

Du Cane Rd, London W12 0NN

London

W12 0NN

United Kingdom

Employer's website